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Treatment Harms in Paediatric Primary Care
David M Reith1, Sharon Leitch2, Kyle Eggleton3
1Dean's Department, Otago Medical School, University of Otago, Dunedin 9016, New Zealand.
Summary
This study found that medication-related harm (MRH) is the most common health system harm in children and adolescents. Increased consultations correlate with a higher risk of harm in this population.
Area of Science:
- Pediatric health outcomes
- Public health surveillance
- Medication safety in youth
Background:
- Health system harms in children are under-documented.
- Understanding pediatric harm epidemiology is crucial for targeted interventions.
- General practice records offer a valuable data source for studying these harms.
Purpose of the Study:
- To determine the epidemiology of health system harms in children and adolescents (≤20 years).
- To identify risk factors associated with these harms.
- To specifically investigate medication-related harm (MRH) in pediatric populations.
Main Methods:
- The SHARP study analyzed 9076 patient records from 44 New Zealand general practices.
- A 3-year study period captured data on "harm" defined as disease, injury, disability, suffering, or death from the health system.
- Epidemiological rates and risk factors were calculated for various harm types, including MRH.
Main Results:
- 193 harms were identified in 141 children and adolescents.
- The overall annualised rate of harm was 36/1000 population.
- Medication-related harm (MRH) was the most frequent type (20/1000), with anti-infectives being the most implicated drug group.
Conclusions:
- Treatment-related harm in children is less frequent than in adults.
- Medication-related harm is the primary type of health system harm in pediatric patients.
- The risk of harm escalates with an increased number of patient consultations.
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