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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:15

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

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Prognostic Factors Associated with Acute Heart Failure in Patients Admitted for COVID-19: Analysis of the

Manuel Méndez Bailón1, Noel Lorenzo Villalba1, Jorge Garcia Onrubia1

  • 1Department of Internal Medicine Hospital Clínico San Carlos, Hospital Clinico San Carlos (IdISSC), 28040 Madrid, Spain.

Journal of Clinical Medicine
|July 29, 2023
PubMed

Insights

Older age, atrial fibrillation, obesity, and peripheral vascular disease are key risk factors for developing heart failure (HF) during COVID-19 hospitalization. Patients with HF faced higher mortality and ICU admission rates.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic has highlighted a significant link with cardiovascular diseases.
  • Heart failure development during COVID-19 infection remains understudied.
  • This research investigates factors predisposing COVID-19 patients to heart failure during hospitalization.

Purpose of the Study:

  • To identify predisposing factors for heart failure (HF) development in hospitalized COVID-19 patients.
  • To analyze the clinical characteristics associated with HF onset during acute COVID-19 infection.
  • To understand the outcomes for COVID-19 patients who develop HF.

Main Methods:

  • Retrospective, multicenter study utilizing the SEMI-COVID-19 Registry.
  • Involved 150 Spanish hospitals and 16,474 COVID-19 patients.
  • Bivariate and multivariate analyses were conducted to identify HF risk factors.

Main Results:

  • 5.8% of hospitalized COVID-19 patients (958/16,474) developed heart failure.
  • Significant risk factors for HF included older age, atrial fibrillation, obesity (BMI > 30 kg/m²), and peripheral vascular disease.
  • Patients developing HF had significantly higher mortality (54.1% vs. 19.1%), intubation rates, and ICU admissions.

Conclusions:

  • Older patients with existing cardiovascular risk factors are more susceptible to developing heart failure during COVID-19.
  • Age, atrial fibrillation, obesity, and peripheral vascular disease are confirmed risk factors for HF in this population.
  • Heart failure development in COVID-19 patients correlates with increased need for intubation and ICU care.
Abstract

Keywords:
COVID-19heart failureprognostic factors

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