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Nocturia and Sleep in Parkinson's Disease.
Ştefania Diaconu1,2, Laura Irincu1,2, Larisa Ungureanu1,2
1Department of Neurology, County Clinic Hospital, 500365 Braşov, Romania.
Journal of Personalized Medicine
|July 29, 2023
Summary
Nocturia affects over 86% of people with Parkinson's disease (PD), significantly worsening sleep quality, fatigue, and overall quality of life for patients.
Area of Science:
- Neurology
- Sleep Medicine
- Urology
Background:
- Nocturia is a common and distressing symptom for individuals with Parkinson's disease (PD).
- Understanding the impact of nocturia on other non-motor symptoms (NMS) is crucial for patient care.
Purpose of the Study:
- To characterize nocturia in people with Parkinson's disease (PwPD).
- To investigate the relationship between nocturia, sleep disturbances, fatigue, and other NMS in PwPD.
Main Methods:
- 130 individuals with PD were assessed using a comprehensive set of validated questionnaires.
- Key assessments included the Non-Motor Symptoms Questionnaire (NMSQ), Parkinson's Disease Sleep Scale (PDSS-2), and Parkinson's Disease Questionnaire (PDQ-39).
Main Results:
- Nocturia was reported by 86.15% of the PwPD cohort.
- Patients with nocturia exhibited significantly worse quality of life (PDQ-39 scores) compared to those without.
- PwPD experiencing nocturia also reported more disturbed sleep and higher scores on fatigue and other NMS scales.
Conclusions:
- Nocturia is highly prevalent in Parkinson's disease.
- Nocturia is strongly associated with impaired sleep, increased fatigue, and a reduced quality of life in PwPD.
- Addressing nocturia may be key to improving overall well-being in Parkinson's patients.
Keywords:
Parkinson’s diseasefatiguenocturianon-motor symptomssleep dysfunctionsurinary tract dysfunctionsMore Related Videos
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