Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

30
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
30
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

27
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
27
Introduction to Electrolytes01:33

Introduction to Electrolytes

10.3K
In humans, electrolytes play a vital role in various physiological processes. Balancing electrolyte levels is essential for normal body functions; their imbalance can be life-threatening. The major electrolytes include sodium, potassium, chloride, calcium, phosphate, and bicarbonate. They are primarily involved in physiological processes, such as nerve signal transmission, membrane trafficking, muscle contraction, buffering body fluids, and balancing water levels in the body.
Role of Sodium
One...
10.3K
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

42
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
42
Roles of Electrolytes: Chloride and Bicarbonate01:29

Roles of Electrolytes: Chloride and Bicarbonate

263
Chloride ions contribute to the osmotic pressure gradient distinguishing the intracellular fluid (ICF) from the extracellular fluid (ECF). They counterbalance positively charged ions in the ECF and ensure its electrochemical stability. The renal system's process of chloride absorption and release generally mirrors that of sodium ions.
Conditions such as hypochloremia can arise from insufficient chloride reabsorption by the kidneys, often compounded by extended bouts of diarrhea, vomiting,...
263
Antihypertensive Drugs: Potassium-Sparing Diuretics01:28

Antihypertensive Drugs: Potassium-Sparing Diuretics

638
Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the functional unit of the kidney. This heightened activity leads to increased sodium reabsorption and excessive excretion of potassium. To counteract this, potassium-sparing diuretics such as amiloride are used. They function by blocking these sodium channels, thereby reducing the influx of sodium into the epithelial cells and minimizing the loss of...
638

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychosocial retrospective follow-up of young adults with congenital adrenal hyperplasia.

European journal of endocrinology·2026
Same author

Psychiatric morbidity following liothyronine exposure in autoimmune hypothyroidism: a Swedish nationwide cohort study.

Journal of the Endocrine Society·2026
Same author

Cardiometabolic Burden in Bilateral Macronodular Adrenal Disease With Primary Aldosteronism.

Hypertension (Dallas, Tex. : 1979)·2026
Same author

Effect of melatonin versus placebo for the prevention of delirium among medically hospitalised older patients: a double-blinded randomised controlled trial (project RESTORE).

BMJ open·2026
Same author

The association of antidepressants with hyponatremia-preventable side effect?

European journal of endocrinology·2026
Same author

Feeding Difficulties and Survival Outcomes in Advanced Dementia: <i>A multicentre retrospective study from Oman</i>.

Sultan Qaboos University medical journal·2026
Same journal

Correction: Iliuta et al. Impact of Pulmonary Hypertension on Mortality After Surgery for Aortic Stenosis. <i>Medicina</i> 2022, <i>58</i>, 1231.

Medicina (Kaunas, Lithuania)·2026
Same journal

Prognostic Value of BUN-Based Ratios for Mortality and Prolonged Hospitalization in Acute Upper Gastrointestinal Bleeding: Comparison with Established Risk Scores.

Medicina (Kaunas, Lithuania)·2026
Same journal

One-Year Comparative Outcomes of Conventional Versus Accelerated Corneal Cross-Linking in Progressive Keratoconus.

Medicina (Kaunas, Lithuania)·2026
Same journal

Beyond the Intestinal Mucosa in Long-Standing Inflammatory Bowel Disease: Consequences of Chronic Inflammation and Endoscopic Approaches to Diagnosis and Management.

Medicina (Kaunas, Lithuania)·2026
Same journal

Biological and Metabolic Correlates of Psychological Resilience in Maintenance Hemodialysis: An Exploratory Gender-Based Study.

Medicina (Kaunas, Lithuania)·2026
Same journal

Influence of Mitral Annular Calcification Assessed by Cardiac Computed Tomography on Procedural and Clinical Outcomes of Transcatheter Aortic Valve Implantation.

Medicina (Kaunas, Lithuania)·2026
See all related articles

Related Experiment Video

Updated: Jul 21, 2025

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
11:43

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

10.5K

Hypermagnesemia in Clinical Practice.

Aya Hasan Aal-Hamad1, Abdullah M Al-Alawi2,3, Masoud Salim Kashoub2,3

  • 1Department of Emergency, Sultan Qaboos University Hospital, P.O. Box 141, Muscat 123, Oman.

Medicina (Kaunas, Lithuania)
|July 29, 2023
PubMed
Summary
This summary is machine-generated.

Hypermagnesemia, or high blood magnesium, is a rare but dangerous condition. Promptly identifying and managing elevated magnesium levels is vital to prevent severe health complications.

Keywords:
clinical practiceelectrolyte disturbancehypermagnesemiahypomagnesemiamagnesium homeostasis

More Related Videos

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
08:47

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Published on: November 8, 2018

11.5K
Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
11:02

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

572

Related Experiment Videos

Last Updated: Jul 21, 2025

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
11:43

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

10.5K
Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
08:47

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Published on: November 8, 2018

11.5K
Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
11:02

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

572

Area of Science:

  • Clinical Medicine
  • Electrolyte Disorders
  • Nephrology

Background:

  • Hypermagnesemia is an uncommon but serious electrolyte imbalance defined by elevated serum magnesium.
  • Magnesium is essential for neuromuscular, cardiac, and metabolic functions.
  • Both hypermagnesemia and hypomagnesemia can lead to significant health issues.

Purpose of the Study:

  • To highlight the clinical significance of hypermagnesemia.
  • To emphasize the importance of early detection and intervention.
  • To outline management and prevention strategies for hypermagnesemia.

Main Methods:

  • Review of clinical literature on hypermagnesemia.
  • Analysis of adverse outcomes associated with elevated magnesium.
  • Discussion of diagnostic and therapeutic approaches.

Main Results:

  • Hypermagnesemia is linked to adverse outcomes, especially in hospitalized patients.
  • Complications include respiratory and cardiovascular issues, neuromuscular dysfunction, and coma.
  • High-risk groups include those with renal impairment or on magnesium supplements.

Conclusions:

  • Early identification and management of hypermagnesemia are critical for patient outcomes.
  • Discontinuation of magnesium therapy, fluid administration, and dialysis are key interventions.
  • Monitoring at-risk patients and prompt intervention are essential for prevention.