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Updated: Jul 20, 2025

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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Multi-Enzymatic Cascade for Efficient Deracemization of dl-Pantolactone into d-Pantolactone

Lijun Jin1, Xun Liu1, Tairan Wang1

  • 1Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.

Molecules (Basel, Switzerland)
|July 29, 2023
PubMed
Summary

A novel three-enzyme cascade efficiently deracemizes dl-pantolactone into d-pantolactone, a key vitamin B5 precursor. This greener method achieves high optical purity using whole-cell biocatalysis.

Keywords:
conjugated polyketone reductasederacemizationdl-pantolactonel-pantolactone dehydrogenasemulti-enzymatic cascade

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