Related Experiment Video

Updated: Jul 20, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

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A First-Class Degrader Candidate Targeting Both KRAS G12D and G12V Mediated by CANDDY Technology Independent of

Etsuko Miyamoto-Sato1,2,3, Satoshi Imanishi3, Lijuan Huang3

  • 1R&D Department, FuturedMe Inc., 2-3-11 Honcho, Nihonbashi, Chuo-ku, Tokyo 103-0023, Tokyo, Japan.

Molecules (Basel, Switzerland)
|July 29, 2023
PubMed

Keywords:
CANDDYKRAS G12DKRAS G12Vcancerchemical knockdowndegradermolecular targeted drugtarget protein degradationundruggable target

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