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Lower Urinary Tract Disorders as Adverse Drug Reactions-A Literature Review
1Department of Clinical Pharmacology, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Pharmaceuticals (Basel, Switzerland)
|July 29, 2023
Summary
Drug side effects can impact the urinary tract, leading to issues like urinary retention and infections. This review details common drug-induced urological disorders and their associated medications.
Area of Science:
- Pharmacology
- Urology
- Internal Medicine
Background:
- Drug side effects are a significant cause of iatrogenic illness.
- Urological complications from systemic drug side effects are underreported.
- Numerous drug classes are implicated in causing lower urinary tract disorders.
Purpose of the Study:
- To characterize drug-induced lower urinary tract disorders.
- To review medications associated with urological side effects.
Main Methods:
- Non-systematic literature review.
- Identification of drug classes and associated urological conditions.
Main Results:
- Anticholinergics, opioid analgesics, NSAIDs, antidepressants, antipsychotics, and certain cardiovascular drugs can cause urinary retention, incontinence, UTIs, and urolithiasis.
- Erectile dysfunction and retroperitoneal fibrosis are also potential drug-induced urological issues.
Conclusions:
- Pharmacotherapy can lead to various urological disorders.
- Awareness of drug-induced urological complications is crucial for patient care.
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