Drug Delivery in Photodynamic Therapy

Francesca Moret1, Greta Varchi2

  • 1Department of Biology, University of Padova, 35100 Padova, Italy.

Pharmaceutics
|July 29, 2023
PubMed
Summary

Photodynamic therapy (PDT) offers a non-invasive treatment for various diseases. This approach utilizes light-activated compounds for targeted cell destruction, showing promise in oncology and beyond.

Related Concept Videos

Drug Delivery: Overview01:16

Drug Delivery: Overview

The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
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Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
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