Acute posterior multifocal placoid pigment epitheliopathy

Five patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE) have been subject to a follow-up study. All the patients had bilateral lesions. The follow-up period ranged from 1 month to 8 years (mean 4 years). All had resumed their previous work, although two patients had severe visual loss in one eye (6/36). No recurrences were observed. Automatic perimetry of the central visual field revealed moderate central scotomata between 5 and 10 db, corresponding to derangement of the pigment epithelium. This may indicate that the pigment derangement may be caused by alterations in the pigment granules in the pigment epithelial cells, and that the pigment epithelial cells have recovered. There were absolute scotomata in two eyes corresponding to chorioretinal atrophy.