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Frequency constraint-based adversarial attack on deep neural networks for medical image classification.

Fang Chen1, Jian Wang1, Han Liu2

  • 1Key Laboratory of Brain-Machine Intelligence Technology, Ministry of Education, Nanjing University of Aeronautics and Astronautics, Nanjing China; College of Computer Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing China.

Computers in Biology and Medicine
|July 29, 2023
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Summary

We developed a new adversarial attack method for AI medical diagnosis systems. This frequency-based approach creates imperceptible attacks across diverse medical images, enhancing AI security.

Keywords:
Adversarial attackFrequency constraintMedical diagnosisPerturbation

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Area of Science:

  • Artificial Intelligence
  • Medical Imaging
  • Cybersecurity

Background:

  • AI systems in medical diagnosis require robust security measures.
  • Adversarial attacks are crucial for testing and improving AI security.
  • Existing attacks struggle with diverse medical imaging modalities and dimensionalities.

Purpose of the Study:

  • To propose a novel, unified adversarial attack method for medical image classification.
  • To ensure imperceptibility and high content similarity in adversarial samples.
  • To address the limitations of existing methods in diverse medical imaging contexts.

Main Methods:

  • A frequency constraint-based adversarial attack method is introduced.
  • Perturbations are injected into high-frequency information, preserving low-frequency details.
  • The method is tested on diverse datasets: 3D CT, 2D X-ray, and 2D ultrasound (breast, thyroid).

Main Results:

  • The proposed method demonstrates superior performance compared to state-of-the-art attacks.
  • Effective adversarial attacks were generated across various medical imaging modalities and dimensionalities.
  • High content similarity and imperceptibility were maintained in attack samples.

Conclusions:

  • The frequency constraint-based method offers a versatile solution for adversarial attacks in medical AI.
  • This approach enhances the security evaluation of AI-driven medical diagnosis systems.
  • The method's adaptability to different medical imaging types is a significant advancement.