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Updated: Jul 20, 2025

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores
Published on: April 5, 2022
Progress in appended calix[4]arene-based receptors for selective recognition of copper ions
Priyanka Kashyap1, Payal Sharma1, Ritu Gohil1
1Department of Chemistry, School of Sciences, Gujarat University, Navrangpura, Ahmedabad-380009, Gujarat, India.
Abstract:
In the past two decades, there has been significant progress in the design and development of synthetic receptors for molecular recognition as they find application in the field of chemical, biological, medical, and environmental sciences. Synthetic receptors based on calix systems appended with fluorogenic and chromogenic groups have gained considerable attention for sensing and recognition of ions and molecules. Copper (Cu2+) is an essential element required in trace amounts in all living organisms to carry out various biological processes. The aim of this review is to summarize advancement in π-conjugated fluorogenic and chromogenic groups appended to calix[4]arene motifs for detection and quantitation of Cu2+ ion. The focus is to present a comprehensive account of extended calix[4]arene systems with different linkers and highlight the unique design and binding characteristics for the recognition and sensing of Cu2+ ions.
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