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Cerebral microbleeds. Utility of SWI sequences
L Martínez Camblor1, J M Peña Suárez1, M Martínez-Cachero García1
1Servicio de Radiodiagnóstico, Hospital Universitario Central de Asturias, Oviedo, Spain.
Radiologia
|July 29, 2023
Summary
Susceptibility-weighted imaging (SWI) is a superior MRI sequence for detecting cerebral microbleeds (CMBs). SWI aids in diagnosing various neurological conditions and serves as a key biomarker in gliomas and multiple sclerosis.
Area of Science:
- Neuroimaging
- Radiology
- Neurology
Background:
- Cerebral microbleeds (CMBs) are small hemorrhages often detected via MRI.
- Identifying CMBs is crucial for diagnosing and managing various neurological disorders.
Purpose of the Study:
- To define cerebral microbleeds (CMBs).
- To identify optimal MRI sequences for CMB detection.
- To review conditions associated with CMBs and the utility of susceptibility-weighted imaging (SWI).
Main Methods:
- Review of MRI sequences for CMB detection.
- Focus on susceptibility-weighted imaging (SWI) and T2* gradient-echo (GRE) sequences.
- Analysis of clinical contexts and conditions associated with CMBs.
Main Results:
- SWI is highly sensitive to magnetic field inhomogeneities caused by substances like blood products.
- SWI demonstrates superior performance in detecting microhemorrhages compared to T2* GRE sequences.
- CMBs are observed in diverse neurological conditions, including gliomas and multiple sclerosis.
Conclusions:
- SWI is an effective MRI sequence for detecting and characterizing microhemorrhages and venous structures.
- SWI is valuable for assessing CMBs in various neurological conditions.
- CMBs are significant biomarkers for glioma status and inflammatory activity in multiple sclerosis.

