Iohexol and metrizoate in urography of insulin dependent patients

A double blind urographic study with the ionic contrast medium metrizoate or the non-ionic medium iohexol was performed on 69 insulin dependent diabetic patients. Metrizoate caused 24 per cent and iohexol 11 per cent mild adverse reactions and metrizoate a significant decrease in creatinine clearance values. Thus iohexol turned out to be better tolerated by these diabetic patients than metrizoate.