First Case of Cupravidus paculus Infection in a Lung Transplant Recipient: A Case Report

Area of Science:

• Medical Microbiology
• Infectious Diseases
• Transplantation Immunology

Background:

• Cupravidus necator is a rare Gram-negative bacterium causing severe infections, primarily in immunocompromised patients.
• This ubiquitous organism resides in diverse environments, including healthcare settings.
• Lung transplant recipients are a vulnerable population for opportunistic infections.

Observation:

• The first documented case of Cupravidus necator infection in a lung transplant recipient is presented.
• The infection necessitated extended antibiotic treatment for complete resolution.
• A comprehensive review of existing literature on C. necator clinical and microbiological profiles was conducted.

Findings:

• Cupravidus necator can cause severe infections in immunocompromised hosts, such as lung transplant recipients.
• Prolonged antibiotic therapy is crucial for eradicating C. necator infections.
• The study identified potential environmental and medical device sources of C. necator.

Implications:

• Highlights the importance of stringent disinfection protocols for medical devices to prevent C. necator transmission.
• Underscores the need for susceptibility testing to guide effective antibiotic treatment strategies.
• Emphasizes the potential for C. necator to cause severe infections in solid organ transplant recipients.