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Modeling the Functional Network for Spatial Navigation in the Human Brain
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Individual-level brain morphological similarity networks: Current methodologies and applications.

Mengjing Cai1, Juanwei Ma1, Zirui Wang1

  • 1Department of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, Tianjin, China.

CNS Neuroscience & Therapeutics
|July 31, 2023
PubMed
Summary

This review summarizes individual-level brain morphological networks, a powerful tool for understanding brain structure. These networks reveal individual brain organization and changes in health and disease.

Keywords:
brain networkindividual levelmorphological similarity networkstructural magnetic resonance imaging

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Area of Science:

  • Neuroscience
  • Neuroimaging
  • Brain Network Analysis

Background:

  • The human brain's complexity necessitates advanced imaging techniques like magnetic resonance imaging (MRI).
  • Structural MRI-based brain morphological networks offer advantages in data acquisition and image quality.
  • These networks reveal intrinsic structural organizing principles of the brain.

Purpose of the Study:

  • To review the methodology and applications of individual-level brain morphological networks.
  • To highlight the significance of individual-level networks in understanding brain structure.
  • To provide insights into brain development and neuropsychiatric disorders.

Main Methods:

  • Focuses on individual-level brain morphological network studies.
  • Introduces various network construction methods.
  • Reviews representative research in the field.

Main Results:

  • Individual-level morphological networks measure regional similarity within single brains.
  • These networks reflect individual brain's morphological information.
  • They have shown significant value in exploring topological brain changes in normal and disease states.

Conclusions:

  • Individual-level morphological networks offer novel perspectives on brain development and disease mechanisms.
  • The review identifies current challenges and future research directions in this field.