Ultrastructural features in active chronic hepatitis with changes resembling Wilson's disease

A case of chronic hepatitis with ultrastructural changes resembling alterations usually occurring in Wilson's disease is presented in an elderly man. At the time of the diagnosis, the patient did not show clinical and laboratory data consistent with the diagnosis of Wilson's disease. Subsequently, the patient developed neurologic symptoms similar to that resulting from hepatolenticular degeneration. The possibility that such lesions are caused by an abnormal copper metabolism in consequence of acquired liver disease is considered.