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MucoUp® as a spacer in brachytherapy for uterine cervical cancer: A first-in-human experience
Yoichi Muramoto1, Naoya Murakami1, Tatsuki Karino1
1Department of Radiation Oncology, Juntendo University Hospital, 3-1-3 Hongo, Bunkyo-ku, Tokyo 113-8431, Japan.
Clinical and Translational Radiation Oncology
|July 31, 2023
Abstract:
We first used MucoUp®, a hyaluronic acid used in endoscopic resection, as a spacer in brachytherapy. In five cervical cancer patients, MucoUp® insertion increased a 90% dose of the high-risk CTV to over 80 Gy while decreasing the dose of organs at risk. No related adverse events were observed.

