Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

152
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
152
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

412
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
412
Causality in Epidemiology01:21

Causality in Epidemiology

477
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
477
Parametric Survival Analysis: Weibull and Exponential Methods01:14

Parametric Survival Analysis: Weibull and Exponential Methods

476
Parametric survival analysis models survival data by assuming a specific probability distribution for the time until an event occurs. The Weibull and exponential distributions are two of the most commonly used methods in this context, due to their versatility and relatively straightforward application.
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
476
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

96
Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
96
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

64
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
64

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

B cells and humoral immunity in melanoma: regulatory and autoimmune-like features and implications for immunotherapy.

Oncoimmunology·2026
Same author

An antibody-drug conjugate designed through clone and isotype selection restricts the growth of CSPG4-expressing triple-negative breast cancer.

NPJ precision oncology·2026
Same author

Phenotypic, functional, prognostic and predictive significance of B-cell and antibody responses in human melanoma: a scoping review.

The British journal of dermatology·2026
Same author

Immunophenotyping TCF1-expressing TILs: spatial profiling and prognostic value in operable non-small cell lung cancer.

Frontiers in immunology·2026
Same author

An Fc-Engineered Glycomodified Antibody Supports Proinflammatory Activation of Immune Effector Cells and Restricts Progression of Breast Cancer.

Cancer research·2025
Same author

Circulating immunoregulatory B cell and autoreactive antibody profiles predict lack of toxicity to anti-PD-1 checkpoint inhibitor treatment in advanced melanoma.

Journal for immunotherapy of cancer·2025
Same journal

A Multi-Agent Reinforcement Learning Framework for Public Health Decision Analysis.

Healthcare analytics (New York, N.Y.)·2026
Same journal

A business retrieval model using scenario planning and analytics for life during and after the pandemic crisis.

Healthcare analytics (New York, N.Y.)·2024
Same journal

SCORECOVID: A Python Package Index for scoring the individual policies against COVID-19.

Healthcare analytics (New York, N.Y.)·2024
Same journal

Competing risks survival data under middle censoring-An application to COVID-19 pandemic.

Healthcare analytics (New York, N.Y.)·2024
Same journal

An explanatory analytics framework for early detection of chronic risk factors in pandemics.

Healthcare analytics (New York, N.Y.)·2023
Same journal

A network analysis and support vector regression approaches for visualising and predicting the COVID-19 outbreak in Malaysia.

Healthcare analytics (New York, N.Y.)·2023
See all related articles

Related Experiment Video

Updated: Jul 20, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

10.7K

A Bayesian predictive analytics model for improving long range epidemic forecasting during an infection wave.

Pedro Henrique da Costa Avelar1,2,3,4, Natalia Del Coco1, Luis C Lamb2

  • 1Data Science Brigade, Porto Alegre, Rio Grande do Sul, Brazil.

Healthcare Analytics (New York, N.Y.)
|July 31, 2023
PubMed
Summary
This summary is machine-generated.

This study introduces improved algorithmic models for predicting COVID-19 deaths, offering more proactive forecasting than existing methods. The new models enhance local policymaking by adapting quickly to changing epidemic trends and accounting for under-reported cases.

Keywords:
Bayesian modelCOVID-19Epidemic forecastingInfection wavePredictive analytics

More Related Videos

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
12:21

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

2.5K
A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

249

Related Experiment Videos

Last Updated: Jul 20, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

10.7K
A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
12:21

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

2.5K
A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

249

Area of Science:

  • Epidemiology
  • Computational modeling
  • Public health

Background:

  • Policymakers faced uncertainty in planning Non-Pharmaceutical Interventions (NPIs) during the early COVID-19 pandemic.
  • Existing epidemiological models were found to be too reliant on manual inputs and slow to adapt to data changes.

Purpose of the Study:

  • To develop and evaluate novel algorithmic models for more accurate and proactive forecasting of epidemic trends.
  • To improve local policymaking by providing reliable predictions amidst uncertainty.

Main Methods:

  • Developed four new models incorporating daily reported deaths and infections.
  • Explicitly addressed missing data, including under-reported cases.
  • Modeled delays in test reporting and simulated weekly death forecasts.
  • Utilized a lighter model variant for faster forecasting post-initialization.

Main Results:

  • Proposed models demonstrated improved forecasting, particularly for long-range predictions and post-peak scenarios.
  • Models showed greater proactivity in identifying trend changes and adapting to post-peak data.
  • Accounting for under-reported cases significantly enhanced model stability.
  • Modeling retroactive data additions had minimal impact on performance.

Conclusions:

  • The developed models offer a more robust and adaptive approach to epidemic forecasting compared to traditional methods.
  • These enhanced predictive tools can better support public health decision-making during epidemics.
  • The models' ability to handle data uncertainties and adapt to trends is crucial for effective NPI planning.