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Primary diffuse large B-cell tumor of the uterus: a case report
1Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.
Frontiers in Medicine
|July 31, 2023
Summary
A rare uterine lymphoma was diagnosed in a postmenopausal woman presenting with a pelvic mass. Chemotherapy with R-CHOP and rituximab led to successful treatment and no recurrence of diffuse large B-cell lymphoma.
Area of Science:
- Gynecologic Oncology
- Hematology
- Oncology
Background:
- Primary diffuse large B-cell lymphoma of the uterus is a rare malignancy.
- It often presents with symptoms mimicking common gynecologic tumors, leading to potential misdiagnosis.
Observation:
- A postmenopausal woman presented with a pelvic mass, showing diffuse uterine enlargement on ultrasound and MRI.
- Initial imaging suggested gynecologic pathology, but lymphoma was considered.
Findings:
- Histological examination confirmed diffuse large B-cell lymphoma of the uterus.
- The patient received R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy and rituximab consolidation therapy.
Implications:
- This case highlights the importance of considering lymphoma in the differential diagnosis of uterine masses.
- Successful treatment with R-CHOP and rituximab demonstrates effective therapeutic options for this rare condition.
