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Updated: Jul 20, 2025

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Necrotizing Soft Tissue Infections of the Breast: A Potentially Lethal Surgical Emergency

Shariful Islam1,2, Aneela Shah1, Anthony Maughn1

  • 1Department of General Surgery, Breast Unit, San Fernando General Hospital, San Fernando, Trinidad and Tobago.

Case Reports in Surgery
|July 31, 2023
PubMed

Necrotizing soft tissue infection (NSTI) of the breast is an extremely rare event in surgical practice. It is considered the most aggressive form of soft tissue infection and a true surgical emergency. It is also associated with a high risk of mortality if not diagnosed promptly. Few cases have been documented in the literature; the exact etiology and risk factors vary from those involving the limbs, trunk, and perineum. Early recognition, prompt surgical treatment, and broad-spectrum antibiotic therapy are crucial for reducing morbidity and mortality. These reports present cases of NSTIs in breasts with unique etiologies and challenges in their management.

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