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An Evidenced-Based Review of Emergency Target Blood Pressure Management for Acute Aortic Dissection
1Department of Vascular Surgery, West China Hospital, 37 Guoxue Alley, Chengdu 610041, Sichuan, China.
Insights
This study summarizes best evidence for emergency blood pressure management in acute aortic dissection. It guides healthcare professionals in developing individualized patient care plans for better outcomes.
Area of Science:
- Emergency Medicine
- Cardiovascular Research
- Evidence-Based Practice
Background:
- Acute aortic dissection requires prompt and precise emergency target blood pressure management.
- Optimal management strategies are crucial for improving patient outcomes and reducing mortality.
- Existing evidence needs synthesis to guide clinical practice effectively.
Purpose of the Study:
- To consolidate the highest quality evidence for emergency target blood pressure management in acute aortic dissection.
- To provide practical guidance for healthcare professionals in emergency settings.
- To support evidence-based decision-making in managing this critical condition.
Main Methods:
- A systematic search of multiple databases and professional association websites was conducted (2010-2022).
- The "6S" evidence pyramid model guided the retrieval of diverse study types (guidelines, RCTs, etc.).
- Evidence rated grade B or higher was evaluated and summarized by two independent researchers.
Main Results:
- Seventeen articles were included, yielding 36 key evidence points across nine topics.
- Key topics covered include target value setting, management strategies, and pharmacological interventions (vasoactive and nonvasoactive drugs).
- Evidence synthesis addressed disease observation, medical history, monitoring, examinations, and patient education.
Conclusions:
- The summarized evidence serves as a vital reference for emergency department physicians and nurses.
- Individualized target blood pressure management plans are recommended for patients with acute aortic dissection.
- Adherence to best evidence is encouraged for optimizing emergency care and patient management.
Objective:
To summarize the best evidence of emergency target blood pressure management for acute aortic dissection and provide guidance for evidence-based practice of emergency target blood pressure management.
Methods:
According to the "6S" evidence pyramid model, the evidence of emergency target blood pressure management of acute aortic dissection in various foreign databases and websites of professional associations from January 1, 2010, to August 1, 2022, was retrieved, including clinical decision-making, guidelines, expert consensus, systematic reviews, randomized controlled trials, cohort studies, and case series. Two researchers used the corresponding document quality evaluation tools to evaluate the documents and extracted and summarized the evidence of documents above grade B.
Results:
A total of 17 articles were included, including 6 clinical decision-making articles, 5 guidelines, 2 expert consensus articles, 1 systematic review article, 1 randomized controlled trial article, 1 cohort study article, and 1 case series article, forming 36 best evidences, including 9 topics, which are target value setting, management strategy, disease observation, medical history collection, monitoring methods, vasoactive drugs, nonvasoactive drugs, related examinations, and patient education.
Conclusion:
The best evidence summarized provides a reference for doctors and nurses in the emergency department to manage the emergency target blood pressure of patients with acute aortic dissection. It is recommended that doctors and nurses in the emergency department follow the best evidence summarized to develop individualized target blood pressure management plan for patients.
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