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Giant right hydronephrosis with underlying double malignancy: a case report.

Shreyas Nellamkuziyil Michael¹, Pirzada Faisal Masood¹, Umesh Sharma¹

¹Department of Urology and Renal Transplant, Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

The Pan African Medical Journal

|July 31, 2023

Summary

This summary is machine-generated.

Giant hydronephrosis, often from ureteropelvic junction obstruction (UPJO), rarely co-occurs with malignancy. This case highlights a rare instance of urothelial carcinoma and incidental renal rhabdomyosarcoma in an adult with giant hydronephrosis.

Keywords:

Bladder tumor case report giant hydronephrosis rhabdomyosarcoma urothelial carcinoma

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Area of Science:

Urology
Oncology
Pathology

Background:

Giant hydronephrosis is typically caused by ureteropelvic junction obstruction (UPJO).
Concurrent malignancy in giant hydronephrosis is uncommon and prone to misdiagnosis.
Early detection and accurate diagnosis are crucial for effective management.

Observation:

A 77-year-old male presented with acute abdominal distension.
Imaging revealed severe right hydronephrosis with renal parenchyma thinning.
Cystoscopy identified a papillary lesion at the right ureteral orifice.

Findings:

Histopathology confirmed low-grade urothelial carcinoma of the ureter.
An incidental pleomorphic rhabdomyosarcoma was found in the kidney.
The patient experienced lung metastasis and died within 6 months.

Implications:

This case underscores the rare co-occurrence of urothelial carcinoma and renal rhabdomyosarcoma in adult giant hydronephrosis.
Diverse clinical presentations necessitate thorough diagnostic evaluation.
Understanding rare pathological findings is vital for improving patient outcomes.