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Published on: September 30, 2021
Endotherapy in pediatric pancreatitis
Nicholas Norris1, David M Troendle
1Division of Pediatric Gastroenterology, University of Texas Southwestern Medical Center, Children's Health, Dallas, Texas, USA.
Insights
Therapeutic endoscopy offers benefits for children with pancreatitis. Advanced procedures like ERCP and EUS-guided therapies are increasingly used, showing promising outcomes and safety in pediatric patients.
Area of Science:
- Pediatric Gastroenterology
- Endoscopic Interventions
Background:
- Pancreatitis in children, including acute recurrent and chronic forms, presents unique challenges.
- Therapeutic endoscopic interventions are emerging as viable treatment options.
Conclusions:
- Therapeutic endoscopy is beneficial for select pediatric pancreatitis cases.
- Further research is needed to optimize patient selection and guide clinical practice.
Purpose Of Review:
Some children with acute recurrent and chronic pancreatitis stand to benefit from therapeutic endoscopic interventions. The purpose of this review is to summarize specific endoscopic therapies used for these conditions and highlight areas of future research.
Recent Findings:
Multicenter collaboration and consortium efforts have provided more data now than ever on the technical outcomes and safety of therapeutic endoscopic procedures for pancreatitis in children. Indications are growing but more research is needed to help guide patient selection.
Summary:
Advanced endoscopic procedures including endoscopic retrograde cholangiopancreatography, endoscopic-ultrasound guided therapies, and single-operator pancreatoscopy may be used in patients with acute recurrent or chronic pancreatitis to manage pancreatic duct obstruction or local complications including pseudocysts and walled-off necrosis. Patient and procedural factors differ between adults and children. Access to these procedures for younger children is growing, and technical outcomes and adverse event rates appear similar between adults and children.
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