Related Experiment Video
Updated: Jul 20, 2025
Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer
Published on: August 20, 2012
Highly Selective Turn-on Fluorescence Sensor for Cd2+ Ions by Tripodal Organic Ligand
Pavankumar Muralakar1, Sasikala Ravi2, Parthasarathy Gayathri2
1Medicinal Organic Chemistry Laboratory, Department of Applied Chemistry, Karunya Institute of Technology and Sciences, Coimbatore, 641 114, Tamil Nadu, India.
Abstract:
Organic fluorescence sensor for selectively detecting and quantifying toxic heavy metal ions has received significant interest due to their environmental hazards. Herein, we have designed and synthesized a simple tripodal Schiff base ligand (1) based on hydroxy-naphthaldehyde and tris(2-aminoethyl)amine (TREN) and demonstrated highly selective turn-on fluorescence sensing of Cd2+ ions. The free ligand did not show any fluorescence in DMF. In contrast, Cd2+ (10- 4 M) addition exhibited a strong enhancement of fluorescence at 450 nm. Interestingly, other metal ions including Zn2+, which exhibit similar chemistry, did not show any turn-on fluorescence. The concentration-dependent studies of 1 with Cd2+ showed the detection limit of 6.78 × 10- 8 M. NMR spectra of 1 with Cd2+ and computational studies were performed to understand the mechanism of sense.
Related Concept Videos
01:14Photoluminescence: Applications
03:02Colors and Magnetism
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...