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How will I recognize you? Insights into endocytic cargo recognition in plants
Andreas De Meyer1, Peter Grones1, Daniel Van Damme1
1Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium; Center for Plant Systems Biology, VIB, 9052 Ghent, Belgium.
Current Opinion in Plant Biology
|July 31, 2023
Summary
This review explores how external signals trigger the internalization of plasma membrane proteins through endocytosis. It details various protein signals and their roles in cellular trafficking.
Area of Science:
- Cell Biology
- Molecular Biology
- Biochemistry
Background:
- The plasma membrane (PM) is crucial for cell-environment interactions, housing diverse proteins.
- External stimuli can trigger selective internalization of PM proteins via endocytosis.
- The coordination and recognition mechanisms of endocytic signals remain largely unknown.
Purpose of the Study:
- To review current knowledge on internalization signals in PM cargo proteins.
- To elucidate the involvement of these signals in protein trafficking.
Main Methods:
- Literature review of endocytosis and protein trafficking.
- Analysis of identified internalization signals in plasma membrane proteins.
Main Results:
- Identified various endocytic signals that mediate protein internalization.
- Highlighted the role of these signals in directing protein trafficking pathways.
Conclusions:
- Understanding these signals is key to deciphering endocytic coordination.
- Further research is needed to fully elucidate signal recognition and trafficking mechanisms.
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