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Sydenham Chorea in Sudan; Presentation Panorama.
Etedal Ahmed A Ibrahim1,2, Rogia Hussein Mohamed3, Khabab Abbasher Hussien Mohamed Ahmed4
1Department of Medicine, Al-Neelain University, Khartoum, Sudan.
Neuropsychiatric Disease and Treatment
|August 1, 2023
Summary
Sydenham
Area of Science:
- Neurology
- Pediatrics
- Rheumatology
Background:
- Sydenham's chorea (SC) is a common childhood neurological disorder.
- It is a complication of streptococcal pharyngitis.
- Understanding its clinical patterns in specific populations is crucial.
Purpose of the Study:
- To determine the clinical pattern of Sydenham's chorea in Sudanese patients.
- To investigate associations with acute rheumatic fever manifestations.
- To analyze laboratory findings in SC patients.
Main Methods:
- A prospective cross-sectional study was conducted.
- Fifty patients diagnosed with Sydenham's chorea were enrolled.
- Data collected via interviews and record reviews using a structured questionnaire.
Main Results:
- The study included 50 patients (70% female, median age 13.7 years).
- Generalized chorea (66%) and dysarthria (70%) were common symptoms.
- Carditis (60%) was prevalent, while erythema marginatum and nodules were absent.
Conclusions:
- Sydenham chorea in Sudan predominantly affects young females.
- Familial predisposition and mitral valve disease are noted tendencies.
- Screening all pediatric chorea patients for SC is recommended.
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