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The association between CHA2DS2-VASc score and aortic valve sclerosis
Funda Başyiğit1, Havva Tuğba Gürsoy1, Özlem Özcan Çelebi1
1Department of Cardiology, Ankara City Hospital, Ankara, Turkey.
Aortic valve sclerosis (AVS) is linked to higher CHA2DS2-VASc scores, indicating increased cardiovascular risk. This finding suggests AVS may serve as a predictor for cardiovascular events in the general population.
Area of Science:
- Cardiology
- Valvular Heart Disease
- Thrombosis
Background:
- Antithrombotic therapy for atrial fibrillation commonly utilizes the CHA2DS2-VASc score.
- Aortic valve sclerosis (AVS) involves aortic valve thickening without motion restriction and is associated with cardiovascular risk factors.
Purpose of the Study:
- To investigate the association between the presence of aortic valve sclerosis (AVS) and the CHA2DS2-VASc score.
Main Methods:
- A cross-sectional, observational study included 411 patients with AVS (grades 1-3) and 102 patients without AVS (grade 0).
- CHA2DS2-VASc scores were compared between patients with and without AVS.
Main Results:
- The group with AVS exhibited significantly higher CHA2DS2-VASc scores compared to the group without AVS (median 3 vs. 1, p < 0.001).
Conclusions:
- Patients with aortic valve sclerosis have a higher CHA2DS2-VASc score.
- AVS may serve as a potential predictor of cardiovascular risk in the general population.
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