Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cycloaddition Reactions: MO Requirements for Photochemical Activation01:12

Cycloaddition Reactions: MO Requirements for Photochemical Activation

2.1K
Some cycloaddition reactions are activated by heat, while others are initiated by light. For example, a [2 + 2] cycloaddition between two ethylene molecules occurs only in the presence of light. It is photochemically allowed but thermally forbidden.
2.1K
Drug Biotransformation: Overview01:16

Drug Biotransformation: Overview

2.5K
Pharmaceutical substances known as xenobiotics are predominantly lipophilic and nonionized. This enables them to permeate lipid bilayers, such as cell membranes, and interact with intracellular target receptors. Lipophilic drugs have an advantage in crossing biological barriers and reaching their intended sites of action. However, lipophilic drugs often have a restricted capacity for renal expulsion or elimination from the body. When these drugs enter the kidneys and undergo glomerular...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simultaneous tuning of the chemical bond rearrangement and interfacial water network reconstruction at iron-doped phosphide/nitride heterostructure for high efficiency hydrogen evolution reaction.

Journal of colloid and interface science·2026
Same author

Correction to "Peptide-Mimicking Poly(2-oxazoline)s Possessing Potent Antifungal Activity and BBB Penetrating Property to Treat Invasive Infections and Meningitis".

Journal of the American Chemical Society·2026
Same author

Customizing Ionic Micelles by Dynamic Coassembly of Sequence-Defined Peptoid Block Copolymers.

Macromolecules·2026
Same author

Intra-arterial thrombolysis as adjunct to endovascular treatment in acute basilar artery occlusion.

Journal of neurology·2026
Same author

Association between different onset types and clinical outcomes in patients with large ischemic stroke following endovascular therapy.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same author

Ion-Sieving Calixarene Fillers Boost Li<sup>+</sup> Transport in Quasi-Solid Electrolytes for High-Loading Lithium Metal Batteries.

Angewandte Chemie (International ed. in English)·2026

Related Experiment Video

Updated: Jul 20, 2025

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
12:31

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

Published on: August 19, 2012

24.5K

Universal and One-Step Modification to Render Diverse Materials Bioactivation.

Qi Chen1,2, Xinyue Zhang2, Donghui Zhang1

  • 1State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.

Journal of the American Chemical Society
|August 1, 2023
PubMed
Summary

Researchers developed a universal, one-step surface modification method to make diverse materials bioactive. This 5-minute dip-coating process enhances cell adhesion for tissue regeneration applications, avoiding color changes associated with other methods.

More Related Videos

Functionalization and Dispersion of Carbon Nanomaterials Using an Environmentally Friendly Ultrasonicated Ozonolysis Process
08:33

Functionalization and Dispersion of Carbon Nanomaterials Using an Environmentally Friendly Ultrasonicated Ozonolysis Process

Published on: May 30, 2017

10.2K
Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
09:27

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

17.4K

Related Experiment Videos

Last Updated: Jul 20, 2025

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
12:31

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

Published on: August 19, 2012

24.5K
Functionalization and Dispersion of Carbon Nanomaterials Using an Environmentally Friendly Ultrasonicated Ozonolysis Process
08:33

Functionalization and Dispersion of Carbon Nanomaterials Using an Environmentally Friendly Ultrasonicated Ozonolysis Process

Published on: May 30, 2017

10.2K
Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
09:27

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability

Published on: April 22, 2016

17.4K

Area of Science:

  • Biomaterials Science
  • Surface Chemistry
  • Tissue Engineering

Background:

  • Bioactive materials are crucial for supporting cell adhesion and tissue regeneration in clinical settings.
  • Surface modification is key to transforming bioinert materials into bioactive ones.
  • A universal, one-step strategy for material bioactivation is urgently needed.

Purpose of the Study:

  • To develop a universal and one-step surface modification strategy for material bioactivation.
  • To demonstrate the efficacy of this strategy using various bioactive molecules.
  • To provide a stable and color-neutral surface modification layer.

Main Methods:

  • A novel one-step dipping method was employed for surface modification.
  • Diverse materials were immersed in solutions containing specific tripeptide-terminated molecules, β-peptide polymers, or RGD peptides.
  • Modification time was optimized to 5 minutes.

Main Results:

  • The strategy successfully rendered diverse materials bioactive with a stable surface modification layer.
  • The process did not induce undesired surface color changes, unlike polydopamine coatings.
  • Material surfaces gained cell adhesion properties without nonspecific protein conjugation.

Conclusions:

  • The developed one-step surface bioactivation strategy is universal and efficient.
  • This method offers a stable, color-neutral approach to enhance material biocompatibility.
  • The strategy holds significant promise for applications in implantable biomaterials and tissue regeneration.