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Updated: Jul 20, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Cardiovascular rhythmicity in overweight and obese children
Catarina Pinto-Silva1, Ana Correia-Costa2,3, Cláudia Moura2,3
1Centro Hospitalar Universitário de Coimbra, Divisão de Pediatria, Coimbra, Portugal.
Obesity in children disrupts cardiovascular rhythmicity, with obese youth showing less 24-hour mean arterial pressure and 8-hour heart rate rhythmicity. This highlights potential early cardiovascular dysregulation in overweight and obese children.
Area of Science:
- Pediatric Cardiology
- Chronobiology
- Public Health
Background:
- Obesity's impact on cardiac rhythmicity in children is understudied.
- Investigating cardiovascular rhythm disturbances in prepubertal children is crucial.
Purpose of the Study:
- To assess how overweight and obesity affect circadian and ultradian cardiovascular rhythmicity in prepubertal children.
- To compare rhythmicity patterns between normal weight and overweight/obese children.
Main Methods:
- Cross-sectional study of 316 children from the Generation XXI birth cohort.
- Utilized 24-hour ambulatory blood pressure monitoring and Fourier analysis.
- Examined circadian and ultradian rhythms of blood pressure (BP) and heart rate (HR).
Main Results:
- Overweight/obese children had a higher prevalence of non-dipping BP patterns (31.5% vs. 21.6%).
- Obese children showed significantly lower prevalence of 24-hour mean arterial pressure (MAP) and 8-hour HR rhythmicity.
- No significant differences were observed in rhythm amplitudes or acrophases between groups.
Conclusions:
- Altered rhythmicity in obese children suggests potential early cardiovascular dysregulation.
- Circadian and ultradian rhythm analysis may serve as sensitive indicators of cardiovascular health in pediatric populations.
- Further research is needed to confirm these findings and explore long-term implications.
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