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Updated: Jul 20, 2025

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Published on: September 16, 2021
Effectiveness of a mixed lifestyle program in couples undergoing assisted reproductive technology: a study protocol
Padideh Malekpour1, Robab Hasanzadeh2, Mojgan Javedani Masroor3
1Shahroud University of Medical Sciences, Shahroud, Iran.
Integrating lifestyle programs into assisted reproductive technology (ART) improves pregnancy and live birth rates. Health-promoting interventions focusing on diet, exercise, and stress management are crucial for couples undergoing fertility treatments.
Area of Science:
- Reproductive Medicine
- Lifestyle Medicine
- Public Health
Background:
- Infertility and assisted reproductive technology (ART) impose significant emotional, financial, and psychological burdens on couples.
- Lifestyle factors including nutrition, physical activity, and stress management critically influence fertility outcomes.
- Current ART interventions in Iran often lack integration with comprehensive lifestyle programs.
Purpose of the Study:
- To investigate the impact of integrated health-promoting lifestyle programs on couples undergoing ART.
- To develop and evaluate a lifestyle intervention tailored for infertile couples utilizing ART.
Main Methods:
- A systematic literature review on health-promoting lifestyles in infertile couples undergoing ART.
- Expert panel consensus to design a lifestyle intervention program (diet, physical activity, stress management).
- A randomized clinical trial comparing the intervention group with a standard care control group, assessing outcomes like pregnancy rates and live birth.
Main Results:
- Health-promoting lifestyle programs are essential for improving pregnancy and live birth rates in ART.
- Integrated programs positively influence fertilization outcomes when combined with in-vitro fertilization (IVF).
- Lifestyle modifications reduce anxiety and stress, leading to healthier pregnancy outcomes.
Conclusions:
- Lifestyle interventions are crucial components of assisted reproductive technologies to enhance fertility success.
- Improving parental health through lifestyle changes contributes to better pregnancy outcomes.
- Coping skills and mental health management are vital for addressing fertility challenges in modern life.
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