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Effect of esketamine nasal drops on pain in children after tonsillectomy using low temperature plasma ablation

Qiu Qian1, Hua Xian Liu2, Yue Qing Li2

  • 1Department of Anesthesiology, Suzhou Wujiang District Children's Hospital, Suzhou, China.

Frontiers in Pediatrics
|August 2, 2023
PubMed

Insights

Esketamine nasal drops effectively reduced pain and accelerated recovery in children post-tonsillectomy with low-temperature plasma ablation. This safe treatment option offers a faster healing process for pediatric patients.

Area of Science:

  • Otolaryngology
  • Pediatric Anesthesiology
  • Pain Management

Background:

  • Tonsillectomy is a common pediatric surgical procedure.
  • Post-tonsillectomy pain management is crucial for patient recovery.
  • Low-temperature plasma ablation is an emerging technique for tonsillectomy.

Purpose of the Study:

  • To evaluate the efficacy of esketamine nasal drops in managing post-tonsillectomy pain in children.
  • To assess the impact of esketamine on recovery time and pseudomembrane formation after tonsillectomy using low-temperature plasma ablation.

Main Methods:

  • A randomized controlled trial involving 76 children undergoing tonsillectomy.
  • Participants were divided into a control group (conventional medication) and a study group (esketamine nasal drops plus routine treatment).
  • Pain levels, pseudomembrane formation, shedding time, and recovery were compared between groups.

Main Results:

  • The esketamine group reported significantly lower pain levels 1-3 days post-surgery.
  • Pseudomembrane formation, shedding-off time, and overall recovery were shorter in the esketamine group (P<0.05).
  • No significant difference in adverse reaction incidence or severity was observed between groups (P>0.05).

Conclusions:

  • Esketamine nasal drops are a safe and effective option for pain management in children after tonsillectomy.
  • This treatment reduces pain and shortens recovery time, improving outcomes for pediatric patients.
  • Low-temperature plasma ablation combined with esketamine nasal drops presents a promising approach to post-tonsillectomy care.
Abstract

Keywords:
childrenesketamine nasal dropslow temperature plasma ablationtonsillar hypertrophytonsillectomy

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