Recent developments in natural biopolymer based drug delivery systems.

Area of Science:

• Biomaterials Science
• Pharmaceutical Sciences
• Nanotechnology

Background:

• Targeted drug delivery to diseased sites remains a significant challenge in medicine.
• Current drug delivery systems (DDS) often struggle with efficacy and systemic toxicity.
• Biopolymers are emerging as advanced materials for innovative DDS.

Purpose of the Study:

• To review recent advancements in biopolymer-based drug delivery systems (DDS).
• To explore the potential clinical applications of these novel DDS.
• To summarize synthesis techniques and formulation strategies for biopolymer DDS.

Main Methods:

• Review of current literature on biopolymer applications in DDS.
• Analysis of various biopolymers including cellulose, chitosan, starch, and proteins.
• Discussion of synthetic techniques for DDS fabrication and formulation.

Main Results:

• Biopolymers exhibit desirable properties like biodegradability, biocompatibility, and high drug loading capacity.
• Biopolymer-based DDS show potential in ocular, dental, transdermal, and intranasal delivery.
• Various synthetic methods enable the creation of tailored biopolymer DDS formulations.

Conclusions:

• Biopolymer-based DDS represent a significant advancement in targeted therapeutic strategies.
• These systems offer enhanced efficacy and reduced toxicity compared to conventional methods.
• Further development holds promise for clinical translation and innovative drug formulations.