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Updated: Jul 20, 2025
08:35
Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
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Renal denervation: recent developments in clinical and preclinical research
Paul Drawz1, Daniel Baumann2, Alex Dayton1
1Department of Medicine, Division of Nephrology and Hypertension.
Current Opinion in Nephrology and Hypertension
|August 2, 2023
Summary
Renal denervation shows promise for hypertension treatment, with ongoing research into its effectiveness and safety. Further studies will identify ideal candidates for this innovative therapy.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Nephrology
Background:
- Renal denervation is an emerging therapeutic approach for managing hypertension.
- Multiple device manufacturers are pursuing FDA approval for renal denervation systems.
- Mechanistic studies are crucial for understanding the impact of renal nerve ablation.
Conclusions:
- Renal denervation consistently demonstrates antihypertensive effects, particularly when medication is withdrawn.
- Further research is needed to elucidate mechanisms and identify patient subgroups who will benefit most.
- Identifying biomarkers is key to optimizing patient selection for renal denervation therapy.
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