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Updated: Jul 20, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Celiac artery thrombosis presenting as acute abdomen
M Sharma1, K Natarajan1, A Mahesh Kumar2
1Department of Gastroenterology, Apollo Hospitals, Greams Road, Chennai, Tamil Nadu, India.
Celiac trunk thrombosis, a rare cause of splenic infarction, can mimic acid reflux symptoms. Prompt diagnosis is crucial for patients with hypercoagulable conditions like antiphospholipid syndrome to prevent severe outcomes.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Hematology
Background:
- Mesenteric vascular thrombosis commonly affects the superior mesenteric artery in hypercoagulable states.
- Isolated celiac artery thrombosis is uncommon and can present with diverse symptoms, including abdominal pain or peptic ulcer-like discomfort.
- Delayed diagnosis of celiac artery thrombosis is linked to significant morbidity and mortality.
Observation:
- A 54-year-old patient with antiphospholipid (APLA) syndrome presented with epigastric pain.
- The patient's symptoms were initially misdiagnosed as acid reflux.
- The underlying cause was identified as splenic infarction due to celiac trunk thrombosis.
Findings:
- This case highlights a rare instance of splenic infarction secondary to celiac trunk thrombosis.
- Antiphospholipid (APLA) syndrome was the identified hypercoagulable condition.
- The clinical presentation mimicked gastrointestinal issues such as acid reflux.
Implications:
- Early recognition of celiac artery thrombosis is vital, even with atypical presentations.
- Consideration of thrombotic events in patients with hypercoagulable conditions is essential.
- This case underscores the importance of a comprehensive diagnostic approach to abdominal pain in at-risk populations.
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