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Updated: Jul 20, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
[Opioid dependent patient with two prescribers]
Martine Kruijtbosch1,2, Elsemiek Jansen-Groot Koerkamp1, Ghislaine van Thiel3
1SIR Institute for Pharmacy Practice and Policy, Leiden.
This study explores a pharmacist's dilemma when a fentanyl-dependent patient receives an oxycodone prescription. It highlights challenges in managing multiple opioid prescribers and ensuring patient safety.
Area of Science:
- Pharmacology
- Medical Ethics
- Patient Safety
Context:
- Rising opioid use, particularly in surgical patients.
- A specific case involving a fentanyl-dependent patient prescribed oxycodone.
- Patient refusal to allow communication with other healthcare providers.
Purpose:
- To analyze a pharmacist's ethical dilemma regarding conflicting opioid prescriptions.
- To explore professional values under pressure in clinical practice.
- To reflect on optimal strategies for managing polypharmacy in opioid use.
Summary:
- A pharmacist faces a dilemma with a fentanyl-dependent patient presenting an oxycodone prescription from a new prescriber.
- The patient objects to the pharmacist contacting their existing prescribers, complicating medication reconciliation.
- The case prompts reflection on professional responsibility, patient autonomy, and medication safety.
Impact:
- Highlights the need for improved communication and collaboration among prescribers.
- Underscores the importance of clear prescribing practices to prevent medication errors.
- Informs best practices for pharmacists managing complex opioid use cases and polypharmacy.
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