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Updated: Jul 20, 2025

Studying Mitochondrial Structure and Function in Drosophila Ovaries
Published on: January 4, 2017
Convergent and divergent mechanisms of peroxisomal and mitochondrial division
Suresh Subramani1, Nandini Shukla1, Jean-Claude Farre1
1Department of Molecular Biology, School of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
Abstract:
Organelle division and segregation are important in cellular homeostasis. Peroxisomes (POs) and mitochondria share a core division machinery and mechanism of membrane scission. The division of each organelle is interdependent not only on the other but also on other organelles, reflecting the dynamic communication between subcellular compartments, even as they coordinate the exchange of metabolites and signals. We highlight common and unique mechanisms involved in the fission of these organelles under the premise that much can be gleaned regarding the division of one organelle based on information available for the other.
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