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Hydroxychloroquine reduces T cells activation recall antigen responses

Monika M Kowatsch1, Julie Lajoie1,2, Lucy Mwangi2

  • 1Laboratory of Viral Immunology, Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.

Plos One
|August 2, 2023
PubMed
Summary

Hydroxychloroquine (HCQ) significantly reduces T cell activation and cytokine production in healthy individuals. This finding is crucial for understanding immune responses in patients with autoimmune diseases undergoing HCQ treatment, particularly concerning vaccine efficacy.

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