Degradation of various amine compounds by mesophilic clostridia

From 60 species of the genus Clostridium tested 26 species were able to degrade one to three of the following compounds: betaine, choline, creatine, and ethanolamine. Degradation of betaine and choline was always associated with the formation of trimethylamine as one of the products. Creatine was converted to N-methylhydantoin and with one species (Clostridium sordellii) to sarcosine in addition. The diagnostic value of the ability of clostridial species to degrade the compounds mentioned is discussed. N,N-dimethylglycine, N,N-dimethylethanolamine or sarcosine were not metabolized by the strains tested.