Related Experiment Video
Updated: Jul 20, 2025

Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform
Published on: January 13, 2019
Cardiovascular disease in space: A systematic review.
Chayakrit Krittanawong1, Ameesh Isath2, Scott Kaplin1
1Cardiology Division, NYU Langone Health and NYU School of Medicine, New York, NY, USA.
Space travel impacts cardiovascular health, causing heart changes and orthostatic intolerance due to microgravity. Space radiation may also increase atherosclerosis risk, requiring further study for long-duration missions.
Area of Science:
- Cardiovascular science
- Space medicine
- Aerospace physiology
Background:
- Expanding commercial space programs necessitate understanding cardiovascular risks.
- Space environmental exposures (microgravity, radiation) pose potential health threats.
- Limited data suggests unique cardiovascular challenges in space compared to Earth.
Conclusions:
- Space hazards significantly impact the cardiovascular system.
- Microgravity induces cardiac atrophy and orthostatic intolerance.
- Space radiation may accelerate atherosclerosis; further research is crucial for long-term missions.
Related Concept Videos
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Regulation of the Cardiovascular System
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
Cardiovascular Drugs: Classification based on Therapeutic Indications
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Overview of the Cardiovascular System
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...

