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Management of hepatitis D in general practice
Carmela Cosentino1, Daniel Clayton-Chubb2, John S Lubel3
1BBiomedSc, MD, Junior Doctor, Basic Physician Trainee at Alfred Health, Department of Gastroenterology and Hepatology, Alfred Health, Melbourne, Vic.
Hepatitis D virus (HDV) coinfection accelerates liver disease in hepatitis B patients. Routine HDV screening and prompt referral for treatment are crucial for managing chronic hepatitis B and preventing severe outcomes.
Area of Science:
- Hepatology
- Virology
- Public Health
Background:
- Hepatitis D virus (HDV) coinfection accelerates liver disease progression in individuals with chronic hepatitis B (CHB).
- HDV infection is associated with increased risks of cirrhosis and hepatocellular carcinoma.
- Approximately 4% of Australians with CHB are coinfected with HDV, with potential underdiagnosis.
Purpose of the Study:
- To emphasize the importance of screening for HDV in CHB patients.
- To provide general practitioners (GPs) with an overview of HDV diagnosis and treatment.
- To reduce liver-related morbidity and mortality in CHB and HDV coinfected individuals.
Main Methods:
- Literature review and clinical guideline synthesis.
- Focus on diagnostic approaches and therapeutic strategies for HDV.
- Emphasis on the role of GPs in patient management.
Main Results:
- Routine HDV screening is recommended for all CHB patients due to diverse risk factors.
- GPs play a critical role in identifying and initiating the diagnostic process for HDV.
- Prompt referral to specialists is advised for considering HDV therapy.
Conclusions:
- Early detection and management of HDV in CHB patients are essential.
- Enhanced GP awareness and screening protocols can improve patient outcomes.
- Addressing HDV underdiagnosis is vital for public health in Australia.
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