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Psammomatoid ossifying fibroma
Abstract:
Fibro-osseous lesions represent a variety of bone proliferations each characterized by different morphologic patterns of osteoid production. Psammomatoid ossifying fibroma (POF) is characterized histologically by numerous small round ossicles resembling psammoma bodies and is a locally invasive lesion of facial and cranial bones. Two cases of POF arising in the ethmoid sinus and involving the orbit are presented to emphasize the importance of complete surgical removal of involved bones. Histologically, portions of POF may demonstrate other patterns of osteoid production, which resemble fibrous dysplasia and Paget's disease of bone. The variation in radiodensity in POF on computed tomography is a function of the density of psammomatoid ossicles and of the coexistence of other "minor" forms of bone proliferation.
Insights
Psammomatoid ossifying fibroma (POF) is a locally invasive bone lesion. Complete surgical removal is crucial for treating POF involving facial bones and the orbit.
Area of Science:
- Oral and Maxillofacial Surgery
- Pathology
- Radiology
Background:
- Fibro-osseous lesions encompass diverse bone proliferations with distinct osteoid production patterns.
- Psammomatoid ossifying fibroma (POF) is a specific type characterized by psammoma body-like ossicles, typically affecting facial and cranial bones.
Observation:
- This study presents two cases of POF originating in the ethmoid sinus and extending into the orbit.
- Histological examination revealed that POF can exhibit varied osteoid production patterns, mimicking fibrous dysplasia and Paget's disease.
Findings:
- Computed tomography (CT) scans show variable radiodensity in POF.
- This variation is attributed to the density of psammomatoid ossicles and the presence of other minor bone proliferation forms.
Implications:
- Complete surgical excision of all affected bone is essential for effective POF management.
- Understanding the varied histological and radiological features of POF aids in accurate diagnosis and treatment planning.