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Extracorporeal Artificial Lungs: Co-Creating Future Technology - A Qualitative Analysis.

Julia Dormann1, Sebastian Wendt1, Michael Dreher2

  • 1Department of Intensive Care Medicine and Intermediate Care, Medical Faculty, RWTH Aachen University, Aachen, Germany.

Medical Devices (Auckland, N.Z.)
|August 3, 2023
PubMed
Summary

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Patient feedback on artificial lungs for advanced lung disease (COPD, PH) is crucial. Early end-user involvement in development is recommended, as patient suffering pressure did not significantly correlate with interest in a portable oxygenator.

Area of Science:

  • Medical Devices
  • Pulmonary Medicine
  • Patient-Reported Outcomes

Background:

  • Advanced lung diseases like COPD and PH significantly reduce quality of life, often necessitating bilateral lung transplantation (bLTx).
  • An artificial portable lung could serve as a bridge to transplantation, enhancing patient mobility and home-based care.
  • Patient acceptance and feedback are vital for advancing the development of such artificial lungs.

Purpose of the Study:

  • To assess patient acceptance of an extracorporeal artificial lung.
  • To integrate patient feedback into the ongoing development of artificial lung technology.
  • To explore the relationship between perceived suffering and the desire for a portable oxygenator.

Main Methods:

  • A portable dummy oxygenator was presented to patients with advanced lung disease.
Keywords:
artificial lungchronic obstructive pulmonary diseasepatient feedbackpulmonary hypertension

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  • Data were collected in Germany and France using online questionnaires and face-to-face interviews.
  • Participant mobility and perceived suffering pressure were assessed.

    • Main Results:

    • 604 participants completed the online questionnaire, and 17 participated in face-to-face interviews.
    • A majority of participants with COPD and PH could walk over 1 km.
    • No statistically significant association was found between suffering pressure and the desire for a portable oxygenator (Fisher's exact test, p=0.45).

    Conclusions:

    • Market introduction of portable oxygenators may face challenges due to the lack of a significant link between suffering and device desire.
    • Early and continuous integration of potential end-users in device development is essential.
    • A mixed-methods approach combining online surveys and interviews proved effective for data collection.