Related Experiment Video
Updated: Jul 20, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Management Practices for Standard-Risk and High-Risk Patients With Bronchiolitis
Derek Spindler1, Kimberly K Monroe1, Mayya Malakh1
1Department of Pediatrics, Division of Pediatric Hospital Medicine, C.S. Mott Children's Hospital.
Insights
Management of bronchiolitis varies, with frequent use of bronchodilators and steroids in both standard-risk and high-risk children, contrary to guidelines. Further research is needed for high-risk patients.
Area of Science:
- Pediatric respiratory medicine
- Clinical trial methodology
Background:
- Bronchiolitis management guidelines recommend supportive care, excluding high-risk patients.
- Varied institutional approaches exist for managing bronchiolitis in children.
Purpose of the Study:
- To describe and compare the management of standard-risk versus high-risk patients with bronchiolitis.
- To evaluate the frequency of diagnostic and therapeutic interventions in different risk groups.
Main Methods:
- Retrospective study of patients under 2 years with bronchiolitis or viral syndrome.
- Patients categorized as standard-risk or high-risk based on established criteria.
- Comparison of diagnostic and therapeutic intervention frequencies between groups.
Main Results:
- 265 patients included: 122 standard-risk (46.0%) and 143 high-risk (54.0%).
- Standard-risk patients received more bronchodilators (65.6% vs 44.1%) and steroids (19.7% vs 14.7%).
- Use of albuterol, hypertonic saline, and chest physiotherapy associated with rapid response team activation.
Conclusions:
- Institutional management of bronchiolitis differs between standard-risk and high-risk children.
- Bronchodilators and steroids are frequently used, irrespective of risk status and guidelines.
- More research is required on effective management strategies for high-risk bronchiolitis patients.
Objective:
Management guidelines for bronchiolitis advocate for supportive care and exclude those with high-risk conditions. We aim to describe and compare the management of standard-risk and high-risk patients with bronchiolitis.
Methods:
This retrospective study examined patients <2 years of age admitted to the general pediatric ward with an International Classification of Diseases, 10th Revision discharge diagnosis code of bronchiolitis or viral syndrome with evidence of lower respiratory tract involvement. Patients were defined as either standard- or high-risk on the basis of previously published criteria. The frequencies of diagnostic and therapeutic interventions were compared.
Results:
We included 265 patients in this study (122 standard-risk [46.0%], 143 high-risk [54.0%]). Increased bronchodilator use was observed in the standard-risk group (any albuterol dosing, standard-risk 65.6%, high-risk 44.1%, P = .003). Increased steroid use was observed in the standard-risk group (any steroid dosing, standard-risk 19.7%, high-risk 14.7%, P = .018). Multiple logistic regression revealed >3 doses of albuterol, hypertonic saline, and chest physiotherapy use to be associated with rapid response team activation (odds ratio [OR] >3 doses albuterol: 8.36 [95% confidence interval (CI): 1.99-35.10], P = .048; OR >3 doses hypertonic saline: 13.94 [95% CI: 4.32-44.92], P = .001); OR percussion and postural drainage: 5.06 [95% CI: 1.88-13.63], P = .017).
Conclusions:
A varied approach to the management of bronchiolitis in both standard-risk and high-risk children occurred institutionally. Bronchodilators and steroids continue to be used frequently despite practice recommendations and regardless of risk status. More research is needed on management strategies in patients at high-risk for severe disease.
Related Concept Videos
Asthma-IV: Nursing Management
First, in...
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
COPD: Management Using Bronchodilators and Corticosteroids
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Chronic Obstructive Pulmonary Disease-V: Nursing Management
Assessment

