Neoadjuvant therapy for HER2-positive acantholytic squamous cell breast carcinoma: a case report
Jia Cong1, HyonSu Jo2,3, Na Zou4
1Department of Breast Surgery, Dalian Women and Children's Medical Group, Dalian, People's Republic of China.
The Journal of International Medical Research
|August 3, 2023
Abstract:
HER2-positive acantholytic squamous cell carcinoma (ASCC) of the breast is exceptionally rare, and its clinicopathologic features are poorly understood. The impact of neoadjuvant therapy on HER2-positive breast ASCC is unclear. Here we report on a 58-year-old woman who was diagnosed with HER2-positive ASCC of the right breast, who underwent neoadjuvant treatment with albumin-paclitaxel, carboplatin, and trastuzumab, and surgery. Neoadjuvant therapy was effective, with no recurrence or metastasis after 1.5 years of postoperative follow-up.
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