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Updated: Jul 20, 2025

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
Published on: March 23, 2011
Predicting aging transition using Echo state network
Biswambhar Rakshit1, Aryalakshmi S1, Arjun J Kartha1
1Department of Mathematics, Amrita School of Physical Sciences, Amrita Vishwa Vidyapeetham, Coimbatore 641112, India.
Abstract:
It is generally known that in a mixture of coupled active and inactive nonlinear oscillators, the entire system may stop oscillating and become inactive if the fraction of active oscillators is reduced to a critical value. This emerging phenomenon, called the "aging transition," can be analytically predicted from the view point of cluster synchronization. One can question whether a model-free, data-driven framework based on neural networks could be used to foretell when such a system will cease oscillation. Here, we demonstrate how a straightforward ESN with trained output weights can accurately forecast both the temporal evaluation and the onset of collapse in coupled paradigmatic limit-cycle oscillators. In particular, we have demonstrated that an ESN can identify the critical fraction of inactive oscillators in a large all-to-all, small-world, and scale-free network when it is trained only with two nodes (one active and the other inactive) selected from three different pre-collapse regimes. We further demonstrate that ESN can anticipate aging transition of the network when trained with the mean-field dynamics of active and inactive oscillators.
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