Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
Intracellular Movement of Viruses and Bacteria01:10

Intracellular Movement of Viruses and Bacteria

Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a virus that...
The Movement of Organelles and Vesicles01:43

The Movement of Organelles and Vesicles

In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The <i>C. elegans</i> nervous system reads the internal state of the hydrogen peroxide-detoxification machinery to trigger escape from this common reactive chemical.

bioRxiv : the preprint server for biology·2026
Same author

<i>Drosophila</i> maintain a consistent navigational goal angle for days to weeks.

bioRxiv : the preprint server for biology·2025
Same author

Whole-brain chemosensory responses of both <i>C. elegans</i> sexes.

bioRxiv : the preprint server for biology·2025
Same author

Type 2 calreticulin mutations activate ATF6 to promote BCL-xL-mediated survival in myeloproliferative neoplasms.

Blood·2025
Same author

Association of Frailty Index and Postoperative Outcomes of Open Bypass Lower Extremity Revascularization for Acute Limb Ischemia Using the Vascular Quality Initiative.

Vascular and endovascular surgery·2024
Same author

Sensory integration of food and population density during the diapause exit decision involves insulin-like signaling in <i>Caenorhabditis elegans</i>.

Proceedings of the National Academy of Sciences of the United States of America·2024

Related Experiment Video

Updated: Jun 5, 2026

C. elegans Tracking and Behavioral Measurement
07:36

C. elegans Tracking and Behavioral Measurement

Published on: November 17, 2012

19.1K

Continuous, long-term crawling behavior characterized by a robotic transport system.

James Yu1, Stephanie Dancausse2, Maria Paz1

  • 1Department of Physics, Northeastern University, Boston, United States.

Elife
|August 3, 2023
PubMed
Summary
This summary is machine-generated.

Researchers developed a robotic system for long-term observation of individual fruit fly larvae behavior. This reveals distinct navigation phenotypes in thermotaxis, previously hidden in population-level studies.

Keywords:
D. melanogasterautomationexplorationnavigationneurosciencephysics of living systems

More Related Videos

Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

6.7K
Manufacturing, Control, and Performance Evaluation of a Gecko-Inspired Soft Robot
07:40

Manufacturing, Control, and Performance Evaluation of a Gecko-Inspired Soft Robot

Published on: June 10, 2020

14.0K

Related Experiment Videos

Last Updated: Jun 5, 2026

C. elegans Tracking and Behavioral Measurement
07:36

C. elegans Tracking and Behavioral Measurement

Published on: November 17, 2012

19.1K
Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

6.7K
Manufacturing, Control, and Performance Evaluation of a Gecko-Inspired Soft Robot
07:40

Manufacturing, Control, and Performance Evaluation of a Gecko-Inspired Soft Robot

Published on: June 10, 2020

14.0K

Area of Science:

  • Neuroscience
  • Ethology
  • Robotics

Background:

  • Behavioral studies are crucial for understanding nervous system function.
  • Current methods limit long-term, continuous observation of individual animal behavior.
  • Developmental dynamics of behavior remain largely uncharacterized in many systems.

Purpose of the Study:

  • To engineer a robotic instrument for long-term, continuous behavioral observation of individual *Drosophila* larvae.
  • To enable detailed locomotion data collection over developmental timescales.
  • To investigate individual larval behavior, including thermotaxis, with unprecedented resolution.

Main Methods:

  • Development of an automated robotic system for tracking and transporting fly larvae within an arena.
  • Implementation of controlled stimulus delivery and continuous measurement capabilities.
  • Long-term (30+ hours) and short-term (6 hours) continuous observation of larval exploratory and search behavior, with and without thermal gradients.

Main Results:

  • The robotic system provides detailed locomotion data over extended periods.
  • Long-term and short-term behavioral dynamics show similar initial patterns.
  • Individual larval thermotaxis revealed a bimodal distribution in navigation efficiency, indicating distinct phenotypes.

Conclusions:

  • The novel robotic system facilitates comprehensive analysis of individual animal behavior and development.
  • Population-level analysis can obscure important individual behavioral variations.
  • This work identifies distinct larval thermotaxis phenotypes, offering new insights into navigation strategies and nervous system function.