Redox signaling and modulation in ageing.
Mehmet Can Atayik1, Ufuk Çakatay2
1Cerrahpasa Faculty of Medicine, Medical Program, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Biogerontology
|August 3, 2023
Summary
Reactive oxygen species (ROS) and redox signaling are crucial for cellular regulation and aging. Understanding adaptive redox homeostasis offers new insights into age-related diseases.
Area of Science:
- Biochemistry
- Cell Biology
- Gerontology
Background:
- Reactive oxygen species (ROS) play a dual role in cellular processes, acting as signaling molecules at physiological levels but causing damage at higher concentrations.
- Redox signaling mechanisms are precisely regulated in various tissues and subcellular locations, influencing critical functions like cell cycle and circadian rhythms.
- Challenges remain in fully understanding the regulatory effects of redox signaling in aging and age-related disorders.
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