Related Experiment Video
Updated: Jun 18, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
A Rare Location of Osteosarcoma in the Cuboid Bone: A Case Report
Nireet Dhillon1, Gayathri Vijayakumar1, Sarah C Tepper1
1Section of Orthopedic Oncology, Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois.
Case:
In this case report, we describe a patient with left foot pain whose magnetic resonance imaging revealed a destructive tumor of the left cuboid bone. A biopsy of the tumor confirmed an osteoblastic osteosarcoma of the cuboid, and the patient was treated with chemotherapy followed by a below-the-knee amputation.
Conclusion:
There are only a handful of cases reporting osteosarcoma of the cuboid bone, and challenges remain in properly diagnosing the lesion to recommend the best course of treatment.
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