An electrochemiluminescence sensor based on the CNTs and CdSe@ZnSe for determination of melamine in milk samples

In this work, a novel electrochemiluminescence (ECL) sensor based on the CdSe@ZnSe and CNTs was constructed for the detection of melamine. CdSe@ZnSe acted as the co-reaction promoter for the enhancement of Ru(bpy)₃²⁺/tri-n-propylamine (TPrA) system and CNTs acted as carriers to immobilize more CdSe@ZnSe. The initial ECL signal significantly amplified due to the synergistic effect of CNTs and CdSe@ZnSe. The ECL signal decreased with the addition of melamine, and the change value of ECL intensity (ΔI) was linearly related to the logarithm of melamine concentration. The constructed ECL sensor was able to detect melamine in the range of 1.0 × 10^-11 - 1.0 × 10^-7 M, and the detection limit was 3.3 × 10^-12 M (S/N = 3). It can be used to detect melamine in milk samples.