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Updated: Jul 20, 2025

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Comparative Analysis of Costs of Caring for Inpatient COVID-19 Patients and Non-COVID-19 Patients at One Academic

Chi-Cheng Huang1, Samuel Rafla2, Jacqueline Lippert1

  • 1From the Department of Internal Medicine, Section of Hospital Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Southern Medical Journal
|August 3, 2023
PubMed

Insights

Caring for patients with coronavirus disease 2019 (COVID-19) is more expensive than for non-COVID patients. This study found higher average daily hospitalization costs for COVID-19 patients, impacting the US healthcare system.

Area of Science:

  • Healthcare Economics
  • Infectious Diseases
  • Hospital Administration

Background:

  • The COVID-19 pandemic has imposed substantial financial strain on the US healthcare system.
  • Understanding the economic impact of COVID-19 hospitalizations is crucial for resource allocation and financial planning.

Purpose of the Study:

  • To compare the direct hospitalization costs between patients with COVID-19 and those with non-COVID-related illnesses.
  • To quantify the difference in average daily costs for admitted patients.

Main Methods:

  • A retrospective cohort study design was employed.
  • Data from Atrium Wake Forest Baptist Hospital (January 2020 - February 2021) were analyzed.
  • Multivariate adjusted linear regression models were used to compare average daily costs.

Main Results:

  • COVID-19 patients had a higher mean average daily direct cost ($1504.01) compared to non-COVID patients ($1341.30).
  • Adjusted analysis revealed an additional direct inpatient cost of $123.00 per day for COVID-19 patients.
  • Total costs, including indirect expenses, could be up to four times greater for COVID-19 cases.

Conclusions:

  • Average daily direct hospital costs are significantly higher for COVID-19 patients.
  • Factors contributing to increased costs include staffing changes and infrastructure needs.
  • Further research with larger, comparable cohorts is recommended to validate these findings.
Abstract

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